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Pure Wellness Medical Supplements

PURE Wellness Sugar Support

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$67.50 USD
Regular price
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$67.50 USD
  • Description
  • Serving size: 3 capsules per day          240 capsules per bottle    80-day supply

    Directions: Take one (1) capsule with each meal or (3) capsules per day with 8-12 fl oz of water daily.

    BENEFITS: Maintain healthy glucose levels with this specially formulated blend of herbs, extracts and vital nutrients. Ingredients have been shown to reduce sugar cravings, lower blood sugar, increase insulin sensitivity, lower cholesterol, and may contribute to weight loss.



    IMPORTANT FACTS:

    BERBERINE: Significantly reduces and stabilizes blood sugar levels in addition to helping the body break down sugars.


    GYMNEMA SYLVESTRE: Reduces sugar cravings and blocks receptors in the intestines (intestines,) decreasing sugar absorption.


    GREEN TEA: Reduces fasting insulin and blood sugar levels, creating better metabolic system function.


    ALPHA-LIPOIC ACID: Potent antioxidant that decreases insulin resistance.


    CINNAMON BARK EXTRACT: Shown to mimic the effects of insulin and increase glucose transport to cells, reduces insulin resistance and lower blood sugar levels.

    VANADYL SULFATE: Showed improvement hepatic and muscle insulin sensitivity, reduces hyperglycemia, insulin resistance and endogenous glucose production

    COQ10: Plays a major role in carbohydrate metabolism, shown to decrease fasting blood sugar ketone bodies, cholesterol levels and high blood pressure and improves heart health.

  • Clinical evidence
  • Many clinical studies show that Berberine can significantly reduce blood sugar levels in individuals with type 2 diabetes (1). Its effectiveness is comparable to the popular diabetes drug metformin (Glucophage) (2) (3). It seems to work via multiple different mechanisms such as decreasing insulin resistance, making the blood sugar lowering hormone insulin more effective, increasing glycolysis, helping the body break down sugars inside cells, decreasing sugar production in the liver, slowing the breakdown of carbohydrates in the gut, and increasing the number of beneficial bacteria in the gut (4). Gymnema sylvestre can help reduce sugar cravings (5,6). Gymnemic acid, a primary component of gymnema helps suppress sweetness by blocking the sugar receptors on your taste buds (5,6). Research shows that Gymnema extracts reduces the ability to taste sweetness and therefore making sweet foods less appealing (5,6). Gymnema is considered to have anti-diabetic properties and has been used in combination with other diabetes medications to lower blood sugar (7). Gymnema blocks receptors in your intestines and thus sugar absorption, lowering your post-meal blood sugar levels (7). Cinnamon has been shown to help insulin do its job by dramatically reducing insulin resistance (8,9). By increasing insulin sensitivity, cinnamon can lower blood sugar levels (8,9). According to a comprehensive review, Green Tea has been associated with decreased fasting glucose levels and A1C levels, as well as reduced fasting insulin levels, which are a measurement of diabetes health (10). Alpha-lipoic acid (ALA) is a potent antioxidant. Some studies suggest it may reduce oxidative stress, lower fasting blood sugar levels, and decrease insulin resistance (11). Cinnamon Bark Extract has been shown to imitate the effects of insulin and increase glucose transport into cells resulting in a lowering of blood sugar (12,13) the effects of which can last at least 12 hours (14). One study found that compounds found in cinnamon have insulin-potentiating properties and may be involved in the alleviation of the signs and symptoms of diabetes and cardiovascular diseases related to insulin resistance and metabolic syndrome (14). Several phenolic compounds found in cinnamon, such as catechin, epicatechin, procyanidin B2, and phenol polymers, all showed significant inhibitory effects on the formation of advanced glycation end products. Their antiglycation activities are not only brought about by their antioxidant activities and are also related to the trapping abilities of reactive carbonyl species (15). That study demonstrated that proanthocyanidins can effectively scavenge reactive carbonyl species, inhibit the formation of advanced glycation end products, and, therefore, have the potential to be developed as agents to alleviate diabetic complications (15). Vanadyl sulfate is a form of vanadium that been shown to improves hepatic and muscle insulin sensitivity, reduce hyperglycemia and insulin resistance in type 2 diabetes mellitus (16). The glucose-lowering effect of vanadyl sulfate correlated well with the reduction in endogenous glucose production (16). Shitega and colleagues studied the effects of CoQ10 administration (17). CoQ10 is a key component of the electron transport chain which plays a major role in carbohydrate metabolism (17). Fasting blood sugar decreased by 31% and ketone bodies decline by 30-59% (17). Shinde et al. suggested CoQ10 supplements may improve heart health and blood sugar and help manage high cholesterol and high blood pressure in individuals with diabetes (18).

  • References
  • 1. Chang W, Chen L, Hatch GM. Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies. Biochem Cell Biol. 2015 Oct;93(5):479-86. doi: 10.1139/bcb-2014-0107. Epub 2014 Dec 1.

    2. Jiarong Lan, Yanyun Zhao, Feixia Dong, Ziyou Yan, Wenjie Zheng, Jinping Fan, Guoli Sun. Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. J Ethnopharmacol 2015 Feb 23;161:69-81. doi: 10.1016/j.jep.2014.09.049. Epub 2014 Dec 10.

    3. Jun Yin 1, Huili Xing, Jianping Ye. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008 May;57(5):712-7. doi: 10.1016/j.metabol.2008.01.013.

    4. Bing Pang 1, Lin-Hua Zhao 2, Qiang Zhou, Tian-Yu Zhao, Han Wang, Cheng-Juan Gu, Xiao-Lin Tong. Application of berberine on treating type 2 diabetes mellitus. Int J Endocrinol. 2015;2015:905749. doi: 10.1155/2015/905749. Epub 2015 Mar 11.

    5. Parijat Kanetkar 1, Rekha Singhal, Madhusudan Kamat. Gymnema sylvestre: A Memoir. J Clin Biochem Nutr. 2007 Sep;41(2):77-81. doi: 10.3164/jcbn.2007010.

    6. P M Brala, R L Hagen. Effects of sweetness perception and caloric value of a preload on short term intake. Physiol Behav. 1983 Jan;30(1):1-9. doi: 10.1016/0031-9384(83)90030-6.

    7. Pragya Tiwari, Khurshid Ahmad, Mohammad Hassan Baig. Gymnema sylvestre for Diabetes: From Traditional Herb to Future's Therapeutic. Curr Pharm Des. 2017;23(11):1667-1676. doi: 10.2174/1381612823666161108162048.

    8. Bolin Qin, M.D., Ph.D., Kiran S. Panickar, Richard A. Anderson, Ph.D., C.N.S. Cinnamon: Potential Role in the Prevention of Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes. J Diabetes Sci Technol. 2010 May; 4(3): 685–693.

    9. Richard A Anderson. Chromium and . polyphenols from cinnamon improve insulin sensitivity. Proc Nutr Soc. 2008 Feb;67(1):48-53. doi: 10.1017/S0029665108006010.

    10. Kai Liu, Rui Zhou, Bin Wang, Ka Chen, Lin-Ying Shi, Jun-Dong Zhu, Man-Tian Mi. Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials. Am J Clin Nutr. 2013 Aug;98(2):340-8. doi: 10.3945/ajcn.112.052746. Epub 2013 Jun 26.

    11. Saeid Golbidi, Mohammad Badran, Ismail Laher. Diabetes and Alpha Lipoic Acid. Front Pharmacol. 2011; 2: 69.

    12. Bolin Qin, M.D., Ph.D., Kiran S. Panickar, Richard A. Anderson, Ph.D., C.N.S. Cinnamon: Potential Role in the Prevention of Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes. J Diabetes Sci Technol. 2010 May; 4(3): 685–693.

    13. Khan A, Bryden NA, Polansky MM, Anderson RA. Insulin potentiating factor and chromium content of selected foods and spices. Biol Trace Elem Res. 1990 Mar; 24(3):183-8.

    14. T P J Solomon 1, A K Blannin. Effects of short-term cinnamon ingestion on in vivo glucose tolerance. Diabetes Obes Metab. 2007 Nov;9(6):895-901.

    15. Peng X, Cheng KW, Ma J, Chen B, Ho CT, Lo C, Chen F, Wang M. Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts. J Agric Food Chem. 2008 Mar 26; 56(6):1907-11.

    16. K Cusi , S Cukier, R A DeFronzo, M Torres, F M Puchulu, J C Redondo. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab. 2001 Mar;86(3):1410-7. doi: 10.1210/jcem.86.3.7337.

    17. Shigeta Y, Izumi K, Abe H. Effect of coenzyme Q7 treatment on blood sugar and ketone bodies of diabetics. J Vitaminol 1966;12:293-298.

    18. Santosh Shinde Ph.D., Neela Patil Ph.D., Anil Tendolkar M.S. Coenzyme Q10: A Review of Essential Functions. The Internet Journal of Nutrition and Wellness 2005 : Volume 1 Number 2