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Pure Wellness Medical Supplements

PURE Wellness Lipid

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$24.50 USD
Regular price
Sale price
$24.50 USD
  • Description
  • Serving size: 1-2 capsules per day    90 capsules per bottle     90 to 45-day supply

    Directions: Take one to two (1-2) capsules with 8-12 fl oz of water daily.

     

    BENEFITS: This powerful combination of natural ingredients is designed to support and encourage healthy cholesterol levels. Evidence shows these ingredients may cause significant reductions in LDL (bad) cholesterol, total cholesterol, and blood triglyceride levels.

     

     

    IMPORTANT FACTS:

    RED YEAST RICE: The most effective cholesterol-lowering nutraceutical on the market. Works to lower cholesterol by inhibiting enzymes that cause an increase in triglycerides, LDL, and total cholesterol levels.

    GINGER: Possesses powerful anti-inflammatory and antioxidant effects to reduce free radicals in the body and lower LDL cholesterol levels.

  • Clinical evidence
  • The extract of Red Yeast Rice (RYR) is the most effective cholesterol-lowering nutraceutical on the market (1). The Red Yeast Rice is created by fermenting yeast (eg, Monascus purpureus, M. pilosus, M. floridanus, M. ruber and, more recently, Pleurotus ostreatus) in red rice (Oryza sativa); the typical red coloration is due to the presence of pigments produced by secondary fermentation (1). monacolin K, which was first isolated by Professor Akira Endo and found to be structurally identical to lovastatin (1). Its primary mechanism of action is to inhibit 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase, the rate-controlling enzyme of the cholesterol synthesis pathway (1). Several meta-analysis and clinical trials have shown the correlation between decreased LDL-C levels and reduction of the relative risk for CVD (2). A meta-analysis performed by the Cholesterol Treatment Trialists' (CTT) Collaboration group that included data from 14 RCTs and 90,056 individuals showed a greater decrease in LDL-C serum concentrations correlated with a greater reduction in vascular and coronary events (3). The positive effect of RYR on laboratory parameters other than LDL-C and on instrumental biomarkers of vascular aging supports its use in patients with moderately elevated LDL-C, especially in primary prevention (4). Ginger contains gingerol which possesses powerful anti-inflammatory and antioxidant effects to help reduce oxidative stress resulting from free radicals in the body (5, 6). In a recent study of people with hyperlipidemia, participants who received ginger-pasted powder each day saw their LDL (bad) cholesterol levels drop by 17.4% over a 3-month period (7).

  • References
  • 1. Arrigo F.G. Cicero, MD, PhD, Federica Fogacci, MS,Maciej Banach, MD, PhD. Red Yeast Rice for Hypercholesterolemia. Methodist Debakey Cardiovasc J. 2019 Jul-Sep; 15(3): 192–199.
    doi: 10.14797/mdcj-15-3-192
    2. Hobbs FD, Banach M, Mikhailidis DP, Malhotra A, Capewell S. Is statin-modified reduction in lipids the most important preventive therapy for cardiovascular disease? A pro/con debate. BMC Med. 2016;14:4.
    3. Baigent C, Keech A, Kearney PM et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005;366(9493):1267–78. ; Cholesterol Treatment Trialists' (CTT) Collaborators.
    4. Cicero AF, Colletti A, Bajraktari G et al. Lipid lowering nutraceuticals in clinical practice: position paper from an International Lipid Expert Panel. Arch Med Sci. 2017;13(5):965–1005.
    5. Shaopeng Wang, Caihua Zhang, Guang Yang, Yanzong Yang. Biological properties of 6-gingerol: a brief review. Nat Prod Commun. 2014 Jul;9(7):1027-30.
    6. Nafiseh Shokri Mashhadi, Reza Ghiasvand, Gholamreza Askari, Mitra Hariri, Leila Darvishi, Mohammad Reza Mofid. Anti-Oxidative and Anti-Inflammatory Effects of Ginger in Health and Physical Activity: Review of Current Evidence. Int J Prev Med. 2013 Apr; 4(Suppl 1): S36–S42.
    7. Shah Murad, Khalid Niaz and Hina Aslam. Effects of Ginger on LDL-C, Total Cholesterol and Body Weight. lin Med Biochem 2018, 4:2